Liverflo contains 4 active and synergistically effective ingredients to improve liver function. The mode of action is both physiological and holistic.

Bio-Active Ingredients: (in a highly absorbed micronized PPC liposome base and delayed release dual capsule technology)

• polyenylphosphatidylcholine (Pharmaceutical Grade PPC) in its highest possible purification grade
• glycyrrhiza glabra of the highest quality provenience with glycyrrhizin as its leading active substance
• silymarin of the highest quality provenience with its key active ingredient silibinin
• s-adenosylmethionine (SAMe) in its highest possible purification grade, as a natural substance for important methylation and metabolic processes in the liver.

The liver is the biochemical factory in the human body, and each of the 4 actives in Liverflo has its own history and special characteristic as a useful and beneficial substance for the liver. Individually and collectively, these active ingredients stimulate the synthesizing, detoxifying, excreting, metabolizing, immunological, and cell membrane activities necessary to healthy liver function.

All four ingredients in LiverFlo are well accepted and administered worldwide. They are well-documented by international pharmacological and clinical investigations, including double-blind studies.

The liver benefiting effects of these frequently administered ingredients are well accepted worldwide. And now these essential liver protective nutrients are delivered in a highly absorbed micronized PPC liposome base and a delayed release capsule inside a capsule (Dual Capsule Technology) delivery system. This combined delivery system significantly increases absorption and bioavailability, and with it, exceptional results. This exciting combination of ingredients and advanced delivery system lead to a specific synergistic and unique mode of action, and to a breakthrough in liver nutrition and function.

4 Clinically Significant and Active Ingredients

• Polyenylphosphatidylcholine (PPC)(100% Purified PhosChol)
• glycyrrhiza glabra (Licorice Root Extract with Highest Available Content Glycyrrhizin (Glycyrrhetinic Acid)
• Silymarin/Silibinin (Milk Thistle)
• S-adenosylmethionine (SAMe)

Why is the combination of the 4 active ingredients in Liverflo so special and why does Liverflo have a synergistic and unique mode of action beyond those described for each ingredient alone?

On the one hand, silymarin and Glycyrrhiza glabra have limited bioavailability, and co-administered PPC in a micronized form increases their lipophilicity to enhance their absorption and bioavailability. The same is the case for SAMe, as its systemic bioavailability is also low after oral administration. However, the patent pending micronized PC emulsion, delivered in a dual capsule with delayed release technology ensures the highest possible absorption of this critical ingredient.

Moreover, experimental and clinical studies have shown additive / synergistic effects of combinations of the active ingredients in Liverflo in comparison with the efficacy of the single active ingredients:

These are exemplary:

• An association between Silymarin and SAMe (Samelive, Fidia/Italy), which has been brought to markets as a registered product.
• A combination of PPC and glycyrrhetinic acid (Phosphogliv, Pharmstandard/Russia) has been successfully registered in Russia and Eastern European Nations.

Clinical studies have demonstrated significant synergistic effects with the combinations of SAMe and DLPC, SAMe and silymarin, silymarin and glycyrrhizin (Glycyrrhiza glabra), and silymarin and PPC. LiverFlo contains all of these special combinations at the appropriate dose quantities and the best possible delivery system available.

A combination of these four bio-active ingredients, delivered to you with superior and patented technology can be considered a new breakthrough in liver nutrition and health.