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PhosChol is the #1 Healthcare Professional Brand of Pharmaceutical Grade PPC
PhosChol is the leading professional brand of pharmaceutical
grade PPC (polyenyl-phosphatidylcholine). In fact, over 100 million
doses have been administered by doctors in the United States alone.
Since 1982, PhosChol has stood alone as the best source of purified
PPC. PhosChol delivers the highest concentrated source of 1,2 DLPC,
which is responsible for PhosChol's superior efficacy.
 Life
happens on the membrane and purified PPC (PhosChol) provides the
building blocks essential to cellular membrane, repair, regeneration and
function.
Like bricks of a
wall, cellular membranes act as barriers to protect each cell and
organelle in the human body, maintaining cellular structure, function
and co-operation.
Membranes are an essential building block for
life as cells, tissues, organs and ultimately an organism cannot be
formed without them.
Without PC and cellular membranes, life as we know it would not be possible.
Phosphatidylcholine clearly plays a vital role in human life.Its role is even more important when unhealthy lifestyle choices are made.Excess
consumption of processed carbohydrates, sugar and HFCS, alcohol, and
drugs, among others, can lead to membrane damage. When cell membranes
become rigid and damaged, function decreases, and health and well-being
is replaced by disease.
When membrane damages are present,
PC is in high demand to help form, proliferate, restore and regenerate
cell membranes and to enhance membrane-dependent metabolism.
With all of the products available to you and/or your patients, why consider PhosChol?
The answer is simple:
- PhosChol's unique mode of action and proven results
- Over 35 years of use in the United States
- Trusted by doctors - Over 100 million doses administered by doctors in the U.S. alone
- Broad and deep clinical documentation
- Gold Standard - 100% purified and pharmaceutical grade polyenylphosphatidylcholine (PPC)
- The highest concentrated source of the cell membrane superstar - 1,2 Dilinoleoylphosphatidylcholine (DLPC - Up To 52%)
- Unsurpassed safety record
- 100 percent satisfaction guarantee
PhosChol: A Membrane Therapeutic for the Liver
According to the intensity of exposure to noxae,
malnutrition or viruses, liver damage may manifest itself as:
- acute and chronic
hepatitis
- fatty liver
- liver cirrhosis
- others
PPC is a superior protectant against liver damage.
Irrespective of the origin, damage to liver cell membranes and to their
organelles is generally present in hepatopathies. Metabolic functions of the
liver cell and the activity of enzymes bound to membranes are inhibited, thus
causing the clinical picture of liver disorders.
References & Areas of Use
References:
- Zierenberg, O. and Grundy, S.M., J. Lipid. Res., 23:1136 (1982).
- Dargel R. et al., Z. Gastroenteral. 29 (Suppl. 2):18 (1991).
- Lekim, D. and Betzing, H., Arzneimit Forsch, 2: 1772 (1976).
- Indovina, J. et al., Epatologica, 27:261 (1981).
- Navder K. P. and Lieber C. S., Biochem. Biophys. Res. Commun. 291:1109 (2002).
- Muting, D. et al., Verh. Dtsch. Ges. innere Med., 78:1389 (1972).
- Kuntz, H. D. it al., Med. Welt., 29:452 (1978).
- Chanussot, F. and Benaoel, L., Life Sciences 73:381 (2003).
- Saratikov A.S. and Vengerovskii A.I., Biull. Eksp. Biol. Med. 127:392 (1999).
- Alliet, J. et al., L'Quest Medical, 29:85 (1976).
- Holecek, M. et al., in: Liver and Drugs 1994 edt. by J. Holoman and J. Glasa. Progress in Hepato-Pharmacol. 1:202 (1995).
PhosChol: Heart Health
PhosChol's primary active ingredient is PPC. Clinical
studies have shown that PPC can help bring the lipid profile into the normal
range.
HDL particles containing PPC, transport 50% more cholesterol
than native HDL particles.
(ZIERENBERG,O. et al: Atherosclerosis 39, 1981, 527)
How HDL particles with PPC transport cholesterol
Which Way Do You Prefer to Manage your Cholesterol?
PPC activates enzyme systems involved in fat metabolism by
mobilizing atherogenic cholesterol from vascular walls and improving
disturbances of fat transport.
PPC is:
- Reliable
- Well tolerated
(even with long term use)
- Effective with
lowest possible risk (no known side effects, interactions, contraindications)
PhosChol: For Diabetes
PhosChol's primary active ingredient is PPC. In clinical
studies, PPC has been shown to have positive effects on plasma lipids and
plasma lipoproteins. Moreover, PPC has been shown to contribute to an improved
condition of blood glucose, glycosylated hemoglobin, ketone body excretion, and
other diabetes-specific parameters by positively affecting the pathological
mechanism of specific diabetes-associated disturbances.
As a Membrane Therapeutic, PPC has been shown to be a
valuable supplement to the basic treatment of diabetics,if controlling the diabetes does not lead to a restoration of
normal lipid metabolism.
PPC has been shown to:
- Have positive
affects on plasma lipids and plasma lipoproteins
- Improve the
lipoprotein profile in diabetic patients
- Influence reverse
cholesterol transport to the liver and may help reduce the consequences of
hyperlipidemia
- Have positive decreasing
effects in some patients to the sensitivity rate of peripheral tissues to INS
- Have positive
effects on incipient peripheral gangrene
- Protect the liver
structures against modification by the aldehydic form of glucose
- Reduce signs of
liver damage due to diabetic related tuberculosis
- Cause positive
increases in plasma lipid levels in the origin of degenerative vascular
complications of diabetes
- Normalize the
energy and lipid metabolism in the liver cell mitochondria
- Hypo-LPE effects
of PPC were observed in decreasing blood cholesterol and triglycerides
- Protects the INS-producing pancreatic cells
Indication: Diabetes-associated dyslipidemia that cannot be
completely normalized by INS or oral antidiabetics, particularly
hypertriglyceridemia and hypoalpha-lipoproteinemia; diabetes-induced
peripheral, coronary and cerebral circulation disturbances.
Dosage Recommendation: 1.8 to 2.7 grams orally. Once daily
at meal time. Take with a little liquid if necessary.
PhosChol: Age Related Memory Loss and Enhanced Brain
Function
There is evidence
that PPC is important for brain health throughout one's life.
PPC is critical
for proper development of important brain areas, including the hippocampus, in
fetuses and infants.
A study involving
college students demonstrated that choline improved memory and cognitive
skills. PhosChol provides the body with a preferred source of choline.
PPC may be
especially important in advanced age because the brain of an older adult takes
less choline into the brain than that of a younger adult. The decrease of PPC
in the brain may play a role in developing age related memory loss, and perhaps
Alzheimer's Disease.
PhosChol: Gastrointestinal Health
The surface of the stomach, known as the mucosal, protects
the stomach wall from the high concentrations of acid and the enzymes present
in the stomach's contents. Without this protection, the stomach wall would be
digested along with the food suspension that the stomach contains.
The PPC in PhosChol
-
Is integrated in
the gastric mucosa
- Significantly
lowers ulceration under treatment by pain medication (NSAID's)
- May relieve pain of patients suffering from
stomachache
PhosChol
Is a natural way
to protect the stomach against exogenous damaging substances like
over-the-counter (OTC) and prescription pain killers, also referred to as
NSAIDs
-
May reduce symptoms
and improve quality of life
- Is a preventive
nutritional food supplement for daily use
- Several European and American research groups have been able
to show that PPC, particularly when it has a high content of essential fatty
acids, can help heal gastric erosions.
Ulcer Index.
PPC is an Essential Component of the Mucosal
Phospholipids, especially PPC, are essential components of
the mucosa. Disorders leading to a reduction in the PPC content, or a
disruption of the PPC membrane cause pain, or in more severe forms, gastric
ulcers or cancer. Disturbances are caused by the following factors: stress,
alcohol, beverages that are too cold, incorrect diet, post gastrointestinal
operations, and reflux of bile from the intestine into the stomach, which
destroy the PPC membrane and, hence, the protective film. Some pain medication often
referred to as non-steroidal anti-inflammatory drugs (NSAIDs) can also cause
significant erosion.
This chart shows the improvement over time of the subjectively-felt
symptoms of 20 patients receiving 3gm of PPC per day.
Fact: PhosChol contains the only Oil Seed Medicinal registered in
two pharmaceutical products registered in over 50 countries around the
world.
Source: National Research Council
of Canada, Ottawa
Why should you consider PhosChol?The answer is simple:
- PhosChol's unique mode of action
- Broad and deep clinical documentation
- The only 100% pure source of Polyenylphosphatidylcholine (PPC)
- The highest concentrated source of Dilinoleoylphosphatidylcholine (DLPC - Up To 52%)
- Pharmaceutical grade quality
- Unsurpassed safety record
- Proven results
- Trusted by doctors. Over 100 million doses have been administered by Doctors in the United States alone, with no known side effects, contraindications, or interactions observed or reported.
- PhosChol is safe and well tolerated even with long-term use.
What do Doctors Have to Say about PhosChol? (Available since 1982 - This is a very short list)
- "Who should consider PhosChol?Anyone with any type of vascular disease,
liver disease, toxin accumulation of any kind, neurological challenges, and
simply to slow the aging process" Dr. Robert Rowen, Second Opinion, Vol. XXII,
No. 5, May 2012
- "The best source of purified phosphatidylcholine (PPC).",
Dr. Sherry Rogers, M.D.
"No More
Heartburn"; 2000.
- "Because it [PhosChol] is part of the membrane sandwich
(along with the right fatty acids and other nutrients), it is one of the
reasons some people will never get better: because no one recommended it."
Dr. Sherry Rogers, M.D., "Detoxify or Die";
2002
- "...These demands keep
me searching for the next anti-aging miracle.
I know I've found it: PPC."Dr.
Nicholas Perricone, M.D., "The Perricone Prescription"; 2002
- "On the basis of a broad range of available clinical trials
EPL/PPC (PhosChol) can be administered in general in membrane associated
damages to enhance cell membrane related physiological processes" Dr. Karl J.
Gundermann, "The Essential Phospholipids as a Membrane Therapeutic", 1993
- FAQ's
- What is PhosChol?
- PhosChol is the first and only, all natural, soy-derived 100 percent pure
source of polyenylphosphatidylcholine (PPC).
PhosChol is an oral therapy for use as a membrane therapeutic. With its
special ingredient 1,2-dilinoleoylphosphatidylcholine (up to 52%) it is
theoretically of importance in all areas in which damaged membrane structures,
reduced phospholipid levels and/or decreased membrane fluidity are present. This
is a hypothesis, which is supported by experimental and clinical investigations
on various membrane-associated disorders and illnesses.
- What is a Phospholipid?
- PhosChol is comprised of pure polyenylphosphatidylcholine, a phospholipid
commonly found in soybean lecithin. Chemically speaking, phospholipids are the
active component in lecithin. Compared to a typical fat or triglyceride
("Tri" meaning three fatty acids attached) phospholipids normally contain two
fatty acids and in place of the third fatty acid they have a phosphorous
containing head group. A phospholipid is unique because its fatty acid tails
like oil and its head group likes water. When a phospholipid comes in contact
with water, it spontaneously forms what is commonly referred to as a bilayer
structure. The bilayer functions as the "skin" or "membrane" of living cells and
organelles.
Another crucial component of a phospholipid is the type of fatty acids
attached to it. A phospholipid such as soy-derived polyenylphosphatidylcholine
is rich in linoleic and linolenic acid, and polyunsaturated fatty acids that
provide "fluidity" to the cell membrane. Maintaining membrane fluidity is
crucial, as the membrane is central to the majority of cellular
activities.
- What is PhosChol most used for?
- Pharmacological investigations, a broad range of clinical trials, and other
available data on PPC and its different modes of action, demonstrate that PPC
acts primarily through its influence on membranes. As cell membrane changes and
damages occur in many disorders, PPC's therapeutic approach in man is a
physiological and holistic one.
Purified PPC aids the body in many ways. It is important to remember that PPC
is an essential nutrient comprising approximately (65%) of every cell membrane
in your body.
PhosChol is often recommended to: (among other uses)
- Help manage and sustain healthy lipid levels
- Provide neuronutrient support
- Help to maintain and improve membrane fluidity
- Support hepatocyte protection, function and regeneration
- Aid in Gastric Mucosa Protection - "Leaky Gut Syndrome" brought on by the
use of NSAIDs, Non Steroidal Anti Inflammatory Drugs like Ibuprofen and Naproxen
- Boost immune system strength
- Purified PPC is commonly used for:
- Acute and chronic hepatitis; cirrhosis; intoxications; fatty degeneration of
the liver of any origin; cholestasis; prophylaxis of gallstone formation;
radiation syndrome; pre-and postoperative care, especially in liver/gallbladder
surgery; dyslipoproteinemia (hypercholesterolemia, hypertriglyceridemia and
hypoalphalipoproteinemia); atherosclerosis; coronary, cerebral, and peripheral
circulatory disturbances; angina pectoris; condition following myocardial
infarction, and apoplexy; hypertension due to sclerosis; vascular diseases,
especially in diabetes mellitus; nephritic syndrome; pre-operative treatment for
the prevention of thrombo-embolism.
- Is PhosChol safe and are there any potential side effects?
From the toxicological investigations, from safety
pharmacology, and from the general pharmacodynamic effects of PPC (the active
substance in PhosChol) it is evident that this extract is safe and non-toxic.
In over fifty years of use, and in thousands of animal and
clinical studies, PPC has been proven safe and reliable.
Over 100 million daily doses have been sold to doctors in
the United States alone, with no known side effects, contraindications, or
interactions. PhosChol is trusted even with long-term use.
No manifestations of intoxication or overdosing have been reported.
There are neither contraindications nor precautions to be observed in the
administration of the preparation.
What if I am taking other medications?
PhosChol is generally well tolerated and can be taken with
other medications. If you are prescribed a medication while taking PhosChol or
wish to take PhosChol while on another medication, it is always best, and we
strongly recommend that you notify your physician.
-
You can request a brochure to show to
your Physician or you can have your physician or primary care giver contact us
for any of their informational needs. We will be happy to assist them.
Doctors who learn about PhosChol usually recommend it.
How much PPC is one dose of PhosChol?- PhosChol has a PPC content of 900mg (~1 gram) per softgel capsule, and
3000mg (~3 grams) per teaspoon in the liquid concentrate.
- Recommended Dosage and Administration
The recommended daily dose is 2-3 capsule - once daily, or 2/3 to a 1 full
tsp. of liquid concentrate - once daily. To be swallowed whole during meals with
a little liquid if required. (PhosChol may be taken on an empty stomach, no
irritability has been reported)
- Is PhosChol safe during Pregnancy?
- PhosChol is often recommended during pregnancy and post pregnancy. As a
nutritional supplement PhosChol is an aid to good health and guards against low
blood choline levels. PhosChol provides a preferred source of highly
bio-available choline.
Because choline is so important in membrane development and repair, it is
transported across the placenta from the mother to the fetus by a 1:14 ratio.
Similarly, the choline concentration in mother's milk is over 100 times the
level in the maternal bloodstream. Thus, the requirement for choline appears to
be especially high in women during pregnancy and lactation. Because of the
heightened requirement for choline, it is likely that both pregnant and
lactating mothers, who are not taking choline supplements, have lower serum
choline concentrations than non-pregnant women.
Given the role of choline in memory and cognitive function and the diversion
of choline from the mother to the fetus, it is speculated that the periodic
lapses in memory and mental acuity often experienced by pregnant and lactating
mothers may be related to lowered choline levels.
- Are There any Similar Products like PhosChol Available in the
Market?
- There are no similar products available in North America. PhosChol is the
only 100% pure source of PPC available in North America. And, only PhosChol
delivers up to 52% dilinoleoylphosphatidylcholine (DLPC). No other product can
compare.
A product similar to PhosChol has been used in Europe as a pharmaceutical
(approved by the Bfarm) for over 50 years. During this time, millions of
Europeans and Asians have enjoyed the healthy membrane therapeutic benefits of
purified PPC. Discover why so many people have added all natural, 100% pure
PhosChol to their daily supplement program.
- I've heard choline in small and in large doses can cause fishy body
order - can this happen with PhosChol
?
- PhosChol is an all natural, soy-derived 100% pure source of
polyenylphosphatidylcholine (PPC). PhosChol provides the body with a preferred
source of bio-available choline and will not cause fish body odor, even at
extremely high doses.
Other products are either phospholipid complexes or choline salts. The
complexes contain only about a third of the PPC in PhosChol. And, the other
phospholipids they contain compete with PPC for absorption.
Choline salts are processed differently by the body than PPC reducing the
actual amount of pure choline available and often resulting in objectionable
fishy body odor.
PhosChol is a natural alternative to synthetic choline salts and can fulfill
the dietary reference or adequate intake (AI) for Choline. And, no energy
consuming Polyenylphosphatidylcholine synthesis from choline is
necessary.
- Is PhosChol A Drug?
- PhosChol is not a drug. PhosChol is an all natural soy-derived dietary
supplement. The United States Food and Drug Administration does not permit
Nutrasal to make any claims regarding the use of PhosChol. In fact, by regulation, we must state in relation to any structure function claims we make:
"These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease."
- Is PhosChol GMO Free?
- The short answer is yes.
View our complete GMO statement
Can't find the answers to your questions? Please Contact Us directly and one of our technical advisors
will be happy to assist you in getting the information you need.
Headed by Dr. Karl J. Gundermann, Nutrasal has an elite group of technical and medical professionals available to answer your product related questions. We have over 35 years of experience with PPC and are able to provide you with the best possible information should you require it. Just Ask Our Experts, and w will get the information you need.
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Product Information
PhosChol is the holistic and physiological way to optimal health and
wellness
Doctor Recommended PhosChol is 100 percent pure
polyenylphosphatidylcholine (PPC), with up to 52% DLPC. In fact, PhosChol delivers
the highest available concentrated source of dilinoleoylphosphatidylcholine
(DLPC). No other product can compare.
We encourage you to take the time to learn about PhosChol
and discover why PhosChol may be just what your body needs.
We recommend speaking with your doctor about the many health
benefits of PhosChol and to determine if PhosChol is right for you. If you are
seeking a safe and proven alternative than PhosChol may be what you are looking
for.
Your doctor may not know about PhosChol and how it may be
able to help you. When speaking with your doctor about PhosChol, we recommend
providing them with a copy of the PhosChol brochure. You can download a copy of
the PhosChol brochure or request a brochure be sent to you.
Most doctors who learn about PhosChol, usually prescribe it
to their patients!
Over 100 million daily doses have been sold to doctors in
the United States alone, with no known side effects, contraindications, or
interactions. PhosChol is trusted even with long-term use.
The Gold Standard
- PhosChol is the
first and only 100% pure source of Polyenylphosphatidylcholine (PPC).
- PhosChol delivers
900mg of purified PPC per softgel capsule, and 3 grams of purified PPC per
measured teaspoon of liquid concentrate.
- PhosChol delivers
more than seven times the PPC content of any other store brand.
- PhosChol contains
up to 52% DLPC.
- PhosChol may enhance
cell membrane related physiological processes.
- PhosChol is
bio-available (greater than 90% absorption), and contains no other phosphatides
that compete for absorption.
- PhosChol is safe
and clinically proven effective.
- PhosChol is trusted
and recommended by doctors.
PhosChol is a 100 percent pure source of
polyenylphosphatidylcholine (PPC) and an oral therapy for use as a membrane
therapeutic. With its special ingredient 1,2-dilinoleoylphosphatidylcholine (up
to 52%), PPC is theoretically of importance in all disorders in which damaged
membrane structures, reduced phospholipid levels and/or decreased membrane
fluidity are present. This hypothesis is supported by experimental and clinical
investigations on various membrane-associated disorders and illnesses.
Pharmacological investigations, a broad range of clinical
trials, and other available data on PPC and its different modes of action,
demonstrate that PPC acts primarily through its influence on membranes. As cell
membrane changes and damages occur in many disorders, PPC's therapeutic
approach in man is a physiological and holistic one.
In numerous clinical studies, purified polyenylphosphatidylcholine
(PPC) has been shown to:
- Help sustain healthy
cardiovascular levels
- Support hepatocyte
protection
- Help maintain
membrane fluidity
- Aid in Gastric
Mucosal Protection (from NSAIDs damage)
- Provide
neuronutrient support
- Boost the immune
system and protect against opportunistic infections
- Improve Physical
Performance
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